Dementia and midlife strategies in your 40s and 50s to combat it

Exercise low and slow

“Just being active is important,” Tabet says. “You don’t have to kill yourself exercising.” But developing habits that are lifelong and consistent is key. “The more you exercise, the more benefit you get.”

Midlife exercising can lead to better brain health later in life, research shows, while other small studies have linked midlife cardiovascular fitness to reduced incidence of dementia in old age. If you struggle to motivate yourself to work out, it may be worth condensing fitness sessions into as few a week as possible because, provided you’re getting the recommended 150 minutes of exercise, fitting that into one three-hour window is the same as six days of half-hourly slots, he says.

“Even if you don’t develop dementia, it might slow down the progression, so I would suggest aerobic exercise for people in their 40s,” Tabet says. Both jogging or power-walking count.

Get no less than seven hours’ sleep

Seven is the magic number for midlife sleepers, says Barbara Sahakian, a professor of clinical neuropsychology at the University of Cambridge. A study she co-authored, charting data from half a million people, found seven hours of sleep was optimal for those middle-aged and older adults.

“Using data from the UK Biobank, we found that those who slept for seven hours consistently had better cognition, including processing speed, visual attention and memory. They also had better mental health.”

Sleep was the lifestyle intervention most likely to reduce the chances of midlife depression, with those who regularly got seven to nine hours’ sleep lowering their risk by 22 per cent.

Cut back on booze (and cigarettes)

There is an “additive effect” to years of too many after-dinner glasses of merlot, Tabet says. He also warns that if you drink or smoke to excess past your 40s, “you’re adding to the burden on the brain” (as well as raising the likelihood of ailments such as high blood pressure and heart and liver disease). Stopping doing so in midlife means “you’re cutting down on the harm by taking action earlier”.

Loading

Join a Zoom call (or a bike club)

“We keep our brains active through engaging in conversations,” says Sahakian. “While doing so, we gain knowledge and use the information stored in our memory, as well as using our social skills to keep the discussion interesting. By having these conversations, we activate neural networks in the brain, so we are ‘using them and not losing them’.” Sahakian advises joining a running or cycle club, or taking up any hobby that might foster connection.

Train your brain

“Learning and remembering are great for the brain and increase the volume of the hippocampus,” Sahakian says. “The hippocampus is important for everyday memory, such as remembering where you left your mobile phone in the house, and this brain area is damaged early on in Alzheimer’s disease.” Tabet says that keeping the brain sharp in midlife – by doing sudokus or crosswords, or by learning a new skill – is always very helpful.

Don’t forget to floss

There is a connection between oral health and the development of dementia through inflammation, Tabet says. Bacteria capable of causing gum disease have been associated with various forms of dementia in research, as the inflammatory molecules the bacteria make can travel from the mouth through the bloodstream and into the brain. While many matters of dementia prevention may be more challenging, oral hygiene and flossing, and brushing your teeth twice a day is simple in warding off gum issues that could more seriously affect midlife health.

Make the most of your health, relationships, fitness and nutrition with our Live Well newsletter. Get it in your inbox every Monday.